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流动与智能化合成研究组

科研成果
发布日期:2025-03-20

1. J. Ruan, S. Li, Z. Wen*. Application of automation and artificial intelligence in flow chemistry[J]. CIESC Journal, 2024, 75(11): 4120-4140.

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Before independent research:

1. A. Slattery,+ Z. Wen,+ P. Tenblad,+ J. Sanjosé-Orduna, D. Pintossi, T. den Hartog, T. Noël*. Automated self-optimization, intensification, and scale-up of photocatalysis in flow. Science, 2024, 383, eadj1817. ( (+Co-First) 

2. L. Capaldo,+ Z. Wen,+ T. Noël*. A field guide to flow chemistry for synthetic organic chemists. Chem. Sci. 2023, 14, 4230-4247. (+Co-First) (Hot paper & Pick of the week). 

3. Z. Wen,+ D. Pintossi,+ M. Nuno, T. Noël*. Membrane-based TBADT recovery as a strategy to increase the sustainability of continuous-flow photocatalytic HAT transformations. Nat. Commun. 2022, 13, 6147. (+Co-First)

4. T. Wan,+ Z. Wen,+ G. Laudadio, L. Capaldo, R. Lammers, J. A. Rincón, P. G. Losada, C. Mateos, M. O. Frederick, R. Broersmad and T. Noël*. Accelerated and Scalable C(sp3)-H Amination via Decatungstate Photocatalysis using a Flow Photoreactor equipped with High-Intensity LEDs. ACS Cent. Sci. 2022, 8, 51–56. (+Co-First) 

5. Z. Wen, T. Wan, A. Vijeta, C. Casadevall, L. Buglioni, E. Reisner* and T. Noël*. Photocatalytic C–H Azolation of Arenes using Heterogeneous Carbon Nitride. ChemSusChem. 2021, 14, 5265-5270. 

6. Z. Wen, A. Maheshwari, C. Sambiagio, Y. Deng, G. Laudadio, K. V. Aken, Y. Sun, H. P. L. Gemoets, T. Noël*. Optimization of a decatungstate-catalyzed C(sp3)-H alkylation using a continuous oscillatory milli-structured photoreactor. Org. Process Res. Dev. 2020, 24, 2356–2361. 

7. Z. Wen, M. Yang, C. Yao, S. Zhao, F. Zhou, G. Chen*. Kinetics study of heterogeneously continuous-flow nitration of trifluoromethoxybenzene. React. Chem. Eng., 2018, 3, 379-387.

8. Z. Wen, F. Jiao, M. Yang, S. Zhao, F. Zhou, G. Chen*. Process development and scale-up of continuous flow nitration of trifluoromethoxybenzene. Org. Process Res. Dev. 2017, 21, 1843-1850. 

9. Z. Dong, S. D. A. Zondag, M. Schmid, Z. Wen, T. Noël*. A meso-scale ultrasonic milli-reactor enables gas-liquid-solid photocatalytic reactions in flow. Chem. Eng. J. 2022, 428, 130968.

10. Z. Dong, Z. Wen, F. Zhao, S. Kuhn, T. Noël*. Scale-up of micro- and milli-reactors: An overview of strategies, design principles and applications. Chem. Eng. Sci. X. 2021, 10, 100097. (Top cited paper)

11. S. Zhao, Z. Dong, C. Yao, Z. Wen, G. Chen*, Q. Yuan. Liquid-liquid two-phase flow in ultrasonic microreactors: cavitation, emulsification and mass transfer enhancement. AIChE J. 2018, 64, 1412-1423. 

12. F. Zhou, B. Zhang, H. Liu, Z. Wen, K. Wang, G. Chen*. Facile preparation of N-alkyl-2-pyrrolidones in a continuous-flow microreactor. Org. Process Res. Dev. 2018, 22, 504-511.

13. F. Zhou, H. Liu, Z. Wen, B. Zhang, K. Wang, G. Chen*. Toward the efficient synthesis of pseudoionone from citral in a continuous-flow microreactor. Ind. Eng. Chem. Res., 2018, 57, 11288-11298. 

 

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